Desecration is a capstone skill on branch 1 of Vex's Vexcalation skill tree in Borderlands 4.

Effects

Phase Explosion and Eldritch Blast create Hazards, dealing Damage over time for a Duration. Eldritch Blast is now Homing. If it hits an airborne enemy, it bursts after a delay, dealing Damage to nearby enemies.

Change History

• The October 2nd, 2025 patch increased hazard damage by 50% and Airborne Burst damage by 48%.